The paradox is that a short-term interruption or reduction of oxygen supply can have positive effects in certain situations.

Hyperbaric oxygen therapy in isolated blood cells can lead to an increase in telomere length and a reduction in age-related changes in the immune system.

HBOT can trigger changes in the transcriptome—the way genes are expressed and activated—in older people. These processes support regenerative processes in the body and can thus contribute to greater health and vitality.

A prospective clinical study shows that hyperbaric oxygen therapy (HBOT) specifically intervenes in the biological processes of skin aging. By improving oxygen supply and activating regenerative mechanisms, signs of skin aging can be slowed and skin health can be supported.

This narrative review summarizes original research on the effectiveness of cryotherapy in relieving chronic pain. The report demonstrates how targeted cold applications can reduce pain and improve the quality of life of those affected.

Whole-body cryotherapy chambers can significantly and clinically relevantly reduce pain and disease activity in rheumatoid arthritis. This also reduces the need for pain medication.

Women with metabolic syndrome and healthy participants underwent 20 whole-body cryotherapy sessions at -130°C. Afterwards, weight, waist circumference, BMI, and fat mass were significantly reduced – particularly in women with metabolic syndrome. The results support the use of whole-body cryotherapy as a complementary therapy for abdominal obesity during menopause.

In fibromyalgia patients, a series of whole-body cryotherapy treatments led to a significant reduction in pain and disease activity after just a few sessions. Simultaneously, changes in cytokine profiles were observed, suggesting an immunomodulatory effect. However, the effect did not persist three months after discontinuation of the therapy. Nevertheless, the majority of patients rated the treatment as important and effective.